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Immunization of Preterm Infants With 10-Valent Pneumococcal Conjugate Vaccine
Pediatrics, 08/20/2011 Omenaca F et al. – Pneumococcal nontypeable Haemophilus influenzae protein D conjugate vaccine (PHiD–CV) was well tolerated and immunogenic in preterm infants when given as a 3–dose primary vaccination, with robust enzyme–linked immunosorbent assay antibody and OPA booster responses in the second year of life. Methods - Three parallel groups of infants received 3-dose primary immunization with PHiD-CV at 2, 4, and 6 months of age and a booster dose at 16 to 18 months: preterm I; preterm II; and term.
- Solicited symptoms and adverse events were recorded.
- Immune responses to PHiD-CV and coadministered vaccine antigens were measured.
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FDA Licenses Sanofi Pasteur’s New Influenza Vaccine Delivered by Intradermal Microinjection – Fluzone® Intradermal (Influenza Virus Vaccine) first to offer an immunization option with 90 percent smaller needle – Swiftwater, Pa — May 10, 2011 /PRNewswire/ — Sanofi Pasteur, the vaccines division of Sanofi (EURONEXT: SAN and NYSE: SNY), announced today the U.S. Food and Drug Administration (FDA) has approved the company’s supplemental biologics license application (sBLA) for licensure of Fluzone Intradermal (Influenza Virus Vaccine). Fluzone Intradermal vaccine is indicated for active immunization of adults 18 through 64 years of age against influenza disease caused by influenza virus subtypes A and type B contained in the vaccine.
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HPV : Indian Scenario Most common cancer in Indian women – Cervical cancer. Incidence – 132,082 (26.7 % of worldwide incidence). worldwide approximately 500,000 women are diagnosed every year Mortality– 74,118 (27% of deaths worldwide). HPV 16 & 18 in women with cervical cancer in India - 76.7%. An increasing trend of genital wart infections in the past few years (HPV 6 & 11 are responsible for 90% of genital warts).
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Antivaccine lobby resists introduction of Hib vaccine in India A campaign against the Haemophilus influenzae type b (Hib) vaccine in India launched by some medical professionals has delayed a government plan to introduce the vaccine through its free national immunisation programme for children. The health ministry had last year announced that it would replace the standard vaccine for diphtheria, pertussis, and tetanus with a pentavalent vaccine that would also protect children against hepatitis B and Hib. The Global Alliance for Vaccines and Immunisation (GAVI), after consultation with the Indian health ministry, had pledged in August 2009 a grant of $165m (£110m; 135m) to roll out the new vaccine to cover 10 million children in 10 of India’s 28 states in 2010. The Hib organism, which can cause severe bacterial meningitis and pneumonia, is estimated to kill more than 370 000 children worldwide each year, GAVI said. Nearly 20% of these deaths occur in India.
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HPV Vaccine Protects Against Anal Infection in Women The bivalent human papillomavirus (HPV) vaccine (Cervarix, GlaxoSmithKline), which is indicated for the prevention of cervical diseases caused by infection with HPV-16 and HPV-18, also provides "strong protection" against anal infection with these HPV types in young women, according to authors of new trial conducted in Costa Rica. The study is the first to show that an HPV vaccine can prevent anal HPV infection in females. However, the protection was not as effective at the anus as it was in the cervix, which was used as a comparator. The women, who were vaccinated at ages 18 to 25 years, were tested 4 years later for anal and cervical HPV-16 and HPV-18 infections to assess the vaccine’s efficacy. In a cohor
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ROTA VIRUS DISEASE Rota virus is the most common cause of severe diarrhea in infants and children Responsible for 27,000 diarrheal deaths each year worldwide Symptoms Incubation period 1 – 3 days Acute watery diarrhea – self-limiting, usually 2 – 7 days, possibly longer Fever - first few days - can be high Vomiting - first few days G1 symptoms may last upto 2 – 3 weeks
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Recommendation for the use of Tdap in HCW In India when we talk about vaccination, more often it is meant for children only, but we forget about the adolescent, Adults, Sick adults Geriatric and above all the respected health care workers who expose their lives to micro-organism and help the community. We forget about these Health Care Workers (HCW) and have no time to think about them and talk on this issue, not even the Gov’t of India bothers. Followings are the provisional recommendation for the use of Tdap in HCW (HCP)
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Dramatic Potential Of Rotavirus Vaccines August 6, 2010, Path reports. New studies reveal dramatic potential of rotavirus vaccines in Asia and Africa Two new studies published today in the Lancet add to a growing body of evidence on the safety, efficacy, and lifesaving potential of rotavirus vaccines in low-income settings of Asia and Africa; where the virus takes its greatest toll. The studies, co-sponsored by the PATH Rotavirus Vaccine Program and conducted at clinical research sites in Ghana, Kenya, Mali, Bangladesh, and Vietnam, found that rotavirus vaccines
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