HPV vaccine is administered in a three-dose series administered by intramuscular injection. The second and third doses should be administered 2 and 6 months after the first dose. The minimum interval between the first and second doses is 4 weeks. The minimum interval between the second and third dose of vaccine is 12 weeks. Doses administered at an interval shorter than the minimum interval should not be counted as valid and should be repeated.
HPV vaccine is given as a 3-dose series:
1st Dose: Now
2nd Dose: 2 months after Dose 1
3rd Dose: 6 months after Dose 1
Additional (booster) doses are not recommended.
If the HPV vaccine schedule is interrupted, the vaccine series does not need to be restarted. If the series is interrupted after the first dose, the second dose should be given as soon as possible, and the second and third doses should be separated by an interval of at least 12 weeks. If only the third dose is delayed, it should be administered as soon as possible.
The vaccine can be administered at the same visit as other age-appropriate vaccines, such as Tdap and quadrivalent meningococcal conjugate (MCV4) vaccines.
HPV vaccine is not approved for use among females younger than 9 years or older than 26 years of age.